• Genomes - the basics
  1. Table of Contents
  2. Genomes
     1. What is a genome?
     2. Where do genomes come from?
  3. DNA
     1. What are genomes made of?
  4. Comparing genomes
     1. How much DNA?
     2. How many chromosomes?
  5. DNA's code
     1. What is DNA's alphabet?
     2. What does DNA code for?
  6. Making proteins
     1. What are proteins made of?
     2. An Example (with codon wheel)
  7. Genes and 'junk'
     1. What does the rest of the DNA do?
  8. Variation
     1. Am I unique?
     2. Can genomes change?
     3. How can mutations cause disease?
     4. Inheriting mutations
  9. Where to next...?
• Genomes - in detail
  1. Table of Contents
  2. In our cells
     1. From microscopes to molecules
  3. DNA: stuff of life
     1. The chemical
     2. DNA structure
     3. From structure to function
  4. Genes: DNA's instructions
     1. What are genes?
     2. Transcription: copying the code
     3. Translating the genetic code
     4. Assembling the protein chain
     5. Folding: Putting proteins to work
  5. Genomes: not just genes
     1. Making molecules
     2. Regulating protein production
     3. Junk?
  6. Many genomes: variation
     1. Am I unique?
     2. Mutations
     3. Mutations: large and small
     4. Mutations: Small changes, big differences
  7. Where to next...?

• The Human Genome Project
  1. Table of Contents
  2. Overview
     1. An immense enterprise
  3. History
     1. Background to big biology
     2. Starting small
  4. Approaches
     1. Approaches to sequencing
  5. Sequencing
     1. Making maps
     2. Making libraries
  6. Sanger method
     1. The sequencing reaction
     2. Detecting the DNA
  7. Publication
     1. A draft
     2. Finishing the sequence
  8. FAQ

• Sequencing centre
  1. Welcome
  2. Sanger sequencing pipeline
     1. Making maps
     2. DNA libraries
     3. Sequencing
     4. Finishing
     5. Accessing information
  3. New sequencing technologies
     1. Sequencing at speed

• Genome Explorer
  1. InsideDNA's Genome Explorer

• Pharmacogenomics
  1. Table of Contents
  2. Background
     1. Just what are pharmacogenomics and pharmacogenetics?
     2. Human genetic variation
     3. Adverse drug reactions because of genetics
     4. Variation in responses to drug treatment
  3. Scientific opportunities
     1. Pharmacogenetics and cancer
     2. From gene to biological 'marker' of disease
  4. Medical use
     1. Pharmacogenetics in action
     2. Abacavir: Pharmacogenetics in practice
     3. Warfarin: Pharmacogenetic potential
  5. Medical challenges
     1. Challenges to overcome
     2. Biobanking and population genomics
  6. Social & ethical issues
     1. Personal genomics
     2. Personal genetic information
• Direct-to-consumer testing
  1. Direct-to-consumer testing
• UK National DNA database
  1. Overview
  2. What the data looks like
  3. Using the database
  4. Taking storing accessing samples
  5. NDNAD benefits
  6. Ethical issues
  7. Further information
• Personal genome sequencing
  1. We're all different
  2. Your genome and your health

• DNA
  1. Zoom in on your genome
  2. Origami DNA
  3. Sequence bracelets
  4. Yummy gummy double helix
  5. What's my name in DNA?
• Proteins
  1. From DNA to protein
• HGP and gene technology
  1. How the human genome was sequenced
  2. DNA libraries - making a BAC library
  3. Subcloning
  4. DNA sequencing
• Cancer
  1. KRAS: Cancer mutation

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