YourGenome.org

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DNA, genes and genomes Human Genome Project Sequencing centre Science spotlights Resources Help Notices Events

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DNA, genes and genomes Introduction General Table of contents Where to next...? Genomes: What is a genome? Where do genomes come from? DNA: What are genomes made of? Comparing genomes: How much DNA? How many chromosomes? DNA's code: What is DNA's alphabet? What does DNA code for? Making proteins: What are proteins made of? An example Genes and 'junk': What does the rest of the DNA do? Variation: Am I unique? Can genomes change? How can mutations cause disease? Inheriting mutations Where to next...? Detailed Table of contents In our cells Where to next...? DNA: stuff of life: The chemical DNA structure From structure to function Genes: DNA's instructions: What are genes? Transcription Translation Assembling Folding Genomes: not just genes: What's in a genome? Making molecules Regulating protein production Junk? Many genomes: variation: Am I unique? Mutations Mutations: large and small Mutations: Small changes ... Where to next...? Human Genome Project Table of contents HGP overview HGP history: HGP background Starting small Approaches: Approaches to sequencing HGP sequencing: Making maps Making libraries Sanger method: Sequencing reaction Detecting the DNA Publication: A draft Finishing the sequence FAQ: FAQ Sequencing centre Overview Sequencing pipeline Making maps DNA libraries Sequencing Finishing Accessing information New technologies Sequencing at speed Science spotlights Understanding common disease Introduction Pharmacogenomics Introduction Background: Pharmacogenomics & pharmacogenetics? Human genetic variation Adverse drug reactions Variation in responses Scientific opportunities: Pharmacogenetics & cancer From gene to biomarker Medical use: Pharmacogenetics in action Abacavir: Pharmacogenetics in practice Warfarin: Pharmacogenetic potential Medical challenges: Challenges to overcome Biobanking and population genomics Social & ethical issues: Personal genomics Personal genetic information Resources Glossary Alphabetical list Ethics and Issues Introduction Direct-to-consumer testing Personal genome sequencing: We're all different Your genome and your health People profiles Table of contents John Burton Phil Butcher Carol Churcher Chris Clee Alison Coffey Tony Cox Richard Durbin Darren Grafham Nancy Holroyd Tim Hubbard Sean Humphray Matthew Jones Karen Oliver Julian Parkhill Michael Quail Jane Rogers Fred Sanger John Sulston Recommended links Genomic links Downloads Contents Site pdfs Animations Activities Video previews Help Introduction About Requirements Navigation Sitemap Notices Copyright Disclaimer Events Cambridge Science Week 2008 Archive Table of contents Cambridge Science Week 2007 BarCamb 2007 Inside DNA