Although cholera is commonly thought to be a disease of the Victorian era, it is still a significant problem in many areas of the modern world. Genomics research is helping to bring us closer to understanding how we may eliminate it once and for all.
Infectious diseases can spread quickly in a hospital environment, particularly if the pathogen that causes the disease is resistant to the drugs relied on to fight it. Genomics may be able to help track these resistant pathogens and nip them in the bud before they become widespread…
The Guinea worm is a water-transmitted parasite that develops over a year in its host before painfully emerging from the skin. It is hoped that it will soon become the first parasite to be eradicated but there are a few challenges to overcome first…
Neglected tropical diseases affect the poorest of the world’s populations but relatively little is known about their biology. Genomics is now providing insight into these diseases and enabling scientists to develop new strategies to prevent and treat these debilitating diseases.
Resistance to antimalarial drugs is one of the biggest problems currently facing malaria control. Recent studies looking at the genome of the malaria parasite could help scientists understand how drug resistance has evolved – and develop the tools needed to keep it in check.
Sequencing the genome of the malaria parasite has revealed interesting clues as to how it is able to evade the human immune system for long enough to cause disease.
In a small number of cases, doctors are able to use pharmacogenomics in their treatment of patients.
Some children with severe combined immunodeficiency (SCID), a genetic disorder characterised by a reduced number of immune cells, have been treated using gene therapy.
Genome-wide association studies have led to the discovery of hundreds of genes with a role in common diseases.
Pharmacogenomics is a specific kind of genetic testing that offers key advantages for doctors trying to choose the best drugs for their patients.
For much of nature, natural selection and ‘survival of the fittest’ still play a dominant role; only the strongest can survive in the wild. As little as a few hundred years ago, the same was true for humans, but what about now?
An adverse drug reaction is when a medication given as instructed and at a normal dose has an unwanted or harmful effect on a patient.
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