Targeting Disease

Some human diseases are due to changes in our DNA. Others are due to invading pathogens. Explore the role our genes play in disease and how scientists are using genetics to develop more effective treatments.  

    Malaria Challenge: Managing Malaria
    Activity

    Take on the role of a programme manager for a community at high risk of malaria and, using the information provided, work out the best strategy for eliminating the disease from the area. 
    Malaria Challenge: Funding Decisions
    Activity

    If you were given £20 million to eradicate malaria, how would you spend it? In this activity you get to find out.
    Build a Bug
    Activity

    Explore the features of two closely related subspecies of the bacteria, Salmonella. Find out how the differences in their genomes results in their ability to cause two very different diseases. 
    BRAF: From Gene to Cancer Therapy
    Activity

    Take on the role of a genome researcher and look at real cancer DNA datasets, taken from cancer patients, to find areas of mutation in the BRAF gene. 
    What is genetic testing?
    Facts

    Genetic testing is an incredibly useful tool for identifying changes or mutations in DNA that could lead to genetic disease. 
    What is cystic fibrosis?
    Facts

    Cystic fibrosis is a relatively common genetic condition in which the lungs and digestive system become clogged with thick, sticky mucus. 
    Is germline gene therapy ethical?
    Debate

    Germline gene therapy targets the reproductive cells, meaning any changes made to the DNA will be passed on to the next generation. Consequently, the practice has dramatically divided opinion.
    Malaria Challenge
    Interactive

    In Malaria Challenge you can explore the different stages of malaria and how scientists are trying to find new ways of preventing and treating this deadly tropical disease.
    Malaria: An Introduction
    Video

    This video introduces you to the disease malaria, taking you through the life cycle of the parasite that causes it and why it is such a huge problem in the developing world.

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