The HGP was a global project.
The Sanger Institute takes its name from the double Nobel Prize winner and ‘father of genomics’, Frederick Sanger.
Dr Francis Collins led the Human Genome Project from 1993. In his work, he was responsible for discovering the genes mutated in cystic fibrosis and Huntington’s disease. He is currently director of the US National Institutes of Health (NIH).
Eric Lander is the founding director of the Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard. He was one of the leaders of the Human Genome Project and his work has been key in developing tools to investigate disease.
It has been over a decade since the Human Genome Project was finished, so what has been happening since and how is the completed human genome sequence being used?
In 2003, two years ahead of schedule, scientists announced that the human genome had been sequenced with an accuracy of 99.99 per cent. It was described as ‘the end of the beginning’.
The announcement of the first draft of the human genome on 26 June 2000 was big news.
The entry of Celera Genomics into the human genome sequencing arena in 1998 galvanised the public effort, leading to a race to sequence the human genome.
The Human Genome Project was a pioneer for encouraging open access to scientific research. In 1996, those involved agreed that all new information produced should be made freely available to all within 24 hours.
Some scientists involved in the Human Genome Project upset the collaborative nature by trying to patent sections of the DNA sequence for their own financial gain.
John Sulston and Bob Waterston led the way for the Human Genome Project after they successfully sequenced the genome of the nematode worm, Caenorhabditis elegans, the first animal to be sequenced.
The Human Genome Project brought scientists together from across the globe. Worldwide collaboration and support was an essential part of the project’s success.
It was a project of such a huge size that no one thought it would be possible at that time, but with the support of key scientists and considerable funding, the Human Genome Project began…
The Human Genome Project, which began officially in 1990, was the largest international collaboration ever undertaken in biology and involved thousands of scientists.
By the mid-1990s, when the Human Genome Project was in full swing, scientists were sequencing DNA using capillary sequencers.
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