In 1984, Alec Jeffreys developed the technique of DNA fingerprinting in his laboratory at the University of Leicester. These techniques have revolutionised the way that the police solve crimes.
Neglected tropical diseases affect the poorest of the world’s populations but relatively little is known about their biology. Genomics is now providing insight into these diseases and enabling scientists to develop new strategies to prevent and treat these debilitating diseases.
In a small number of cases, doctors are able to use pharmacogenomics in their treatment of patients.
Resistance to antimalarial drugs is one of the biggest problems currently facing malaria control. Recent studies looking at the genome of the malaria parasite could help scientists understand how drug resistance has evolved – and develop the tools needed to keep it in check.
Sequencing the genome of the malaria parasite has revealed interesting clues as to how it is able to evade the human immune system for long enough to cause disease.
How was DNA discovered to be the carrier of genetic information? Read on to find out...
The zebrafish (Danio rerio) has become a popular model organism only relatively recently. It is a tropical fish from the minnow family with a genetic structure surprisingly similar to ours.
The mouse is closely related to humans with a striking similarity to us in terms of anatomy, physiology and genetics. This makes the mouse an extremely useful model organism.
Yeast is one of the simplest eukaryotic organisms but many essential cellular processes are the same in yeast and humans. It is therefore an important organism to study to understand basic molecular processes in humans.
While many species of amphibians have been studied by scientists, the one that stands out in genetics is the African clawed frog, Xenopus laevis.
It has been over a decade since the Human Genome Project was finished, so what has been happening since and how is the completed human genome sequence being used?
The Human Genome Project was a pioneer for encouraging open access to scientific research. In 1996, those involved agreed that all new information produced should be made freely available to all within 24 hours.
John Sulston and Bob Waterston led the way for the Human Genome Project after they successfully sequenced the genome of the nematode worm, Caenorhabditis elegans, the first animal to be sequenced.
With third generation sequencing, sequencing a genome has become a cheaper, faster and more sophisticated process.
The Sanger sequencing method, developed in 1977, enabled scientists to read the genetic code for the first time. It is based on the natural process of DNA replication.
DNA sequencing is the process of working out the order of the bases, A, C, G and T, in a strand of DNA.
The 1950s and early 1960s saw a dazzling explosion in molecular biology. The structure of DNA had been uncovered and the mysteries of biology seemed eminently solvable. What would be the next big thing?
The fruit fly, also known as Drosophila melanogaster, has the longest history in genetics and research out of all the model organisms.
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