Research

Research

stories The ‘eureka’ moment that revolutionised crime solving In 1984, Alec Jeffreys developed the technique of DNA fingerprinting in his laboratory at the University of Leicester. These techniques have revolutionised the way that the police solve crimes.
stories How is genomics being used to tackle neglected tropical diseases? Neglected tropical diseases affect the poorest of the world’s populations but relatively little is known about their biology. Genomics is now providing insight into these diseases and enabling scientists to develop new strategies to prevent and treat these debilitating diseases.
stories The ongoing battle against drug resistant malaria Resistance to antimalarial drugs is one of the biggest problems currently facing malaria control. Recent studies looking at the genome of the malaria parasite could help scientists understand how drug resistance has evolved – and develop the tools needed to keep it in check.
stories Malaria: the master of disguise Sequencing the genome of the malaria parasite has revealed interesting clues as to how it is able to evade the human immune system for long enough to cause disease.
stories Revealing DNA as the molecule of life How was DNA discovered to be the carrier of genetic information? Read on to find out...
stories Using yeast in biology Yeast is one of the simplest eukaryotic organisms but many essential cellular processes are the same in yeast and humans. It is therefore an important organism to study to understand basic molecular processes in humans.
stories How is pharmacogenomics being used? In a small number of cases, doctors are able to use pharmacogenomics in their treatment of patients.
stories Of mice and men The mouse is closely related to humans with a striking similarity to us in terms of anatomy, physiology and genetics. This makes the mouse an extremely useful model organism.
stories The African clawed frog While many species of amphibians have been studied by scientists, the one that stands out in genetics is the African clawed frog, Xenopus laevis.
stories How is the completed human genome sequence being used? It has been over a decade since the Human Genome Project was finished, so what has been happening since and how is the completed human genome sequence being used?
stories How did the Human Genome Project make science more accessible? The Human Genome Project was a pioneer for encouraging open access to scientific research. In 1996, those involved agreed that all new information produced should be made freely available to all within 24 hours.
stories The pilot project for the Human Genome Project: C. elegans John Sulston and Bob Waterston led the way for the Human Genome Project after they successfully sequenced the genome of the nematode worm, Caenorhabditis elegans, the first animal to be sequenced.
stories Pacbio and third generation sequencing With third generation sequencing, sequencing a genome has become a cheaper, faster and more sophisticated process.
stories The dawn of DNA sequencing The Sanger sequencing method, developed in 1977, enabled scientists to read the genetic code for the first time. It is based on the natural process of DNA replication.
stories What is DNA sequencing? DNA sequencing is the process of working out the order of the bases, A, C, G and T, in a strand of DNA.
stories Sequencing the worm The 1950s and early 1960s saw a dazzling explosion in molecular biology. The structure of DNA had been uncovered and the mysteries of biology seemed eminently solvable. What would be the next big thing?
stories Fruit flies in the laboratory The fruit fly, also known as Drosophila melanogaster, has the longest history in genetics and research out of all the model organisms.
stories Tiny fish, big splash: the story of the zebrafish The zebrafish (Danio rerio) has become a popular model organism only relatively recently. It is a tropical fish from the minnow family with a genetic structure surprisingly similar to ours.

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